This study examined the moderating role of organizational culture on the relationship between ethical managerial practices and organizational resilience in tertiary health institutions in Bayelsa State. The study used a cross sectional research design involving directors and heads of departments of the Federal Medical Centre, Yenagoa and Niger Delta University Teaching Hospital, Kolobiri. The primary source of data collection was through the structured questionnaire .The sampling elements in the population consist of 113 directors and heads of department of both hospitals. The entire population elements are included in the study therefore no sample size was determined. After data cleaning, only data of 83 respondents were finally used for data analysis. Descriptive statistics and Spearman’s Rank Order Correlation was used for data analysis and hypothesis testing. The study findings confirmed that organizational culture has a moderating role on the relationship between ethical managerial practices and organizational resilience in tertiary health institutions in Bayelsa State. The study recommended that management of tertiary institutions should Management should pay attention to strict adherence to ethical principles for a sound ethical culture. Management should ensure the installation of an active internet and communication technology facility for an up-to-date resilience building