This study focused on knowledge of hygiene among abattoir management workers in Delta Central Senatorial District, Nigeria. The population for this study comprised of all slaughterhouse workers in Delta Central Senatorial District. Descriptive cross-sectional survey design was adopted for the study. The sample size was seven hundred and sixty respondents. Data was collected using a self-structured questionnaire with a reliability coefficient of 0.76 and was analyzed using descriptive statistics such as frequencies, percentages, mean, standard deviation while ANOVA and logistic regression test was used for testing the hypotheses at 0.05 level of significance. The finding of the study revealed that majority of the 629(83.1%) had good knowledge of abattoir management while less than one quarter 128(16.9%) had poor knowledge. The tested hypotheses revealed there were significant relationship between training and knowledge of abattoir management (p<0.05), years of work experience and knowledge of abattoir management (p<0.05), age and knowledge of abattoir management (p<0.05) among slaughterhouse workers. It was concluded that abattoir workers needs intervention strategies to sustain the level of knowledge of good abattoir management. It recommended amongst others that training should be given to abattoir workers by the Government, management and relevant stakeholders in areas of management and control measures to minimize risks improve adherence to occupational safety.