The study assessed the effect of effective risk communication on nursing performance while evaluating the moderating role of social media usage on the risk communication-performance relationship. The study was cross-sectional. Three purposefully selected public hospitals' 371 nurses in Ghana were surveyed online. The findings revealed that effective risk communication positively influenced nursing performance. An analysis of social media usage as a moderator revealed that the use of social media positively moderated the risk communication performance relationship. The study adds to the literature on nursing performance modeling by introducing novel antecedents to improve nursing performance. It offers nursing managers knowledge on alternative ways to improve nurses’ performance. It provides nurses and nursing managers with insight into the positive effects of incorporating social media usage into their daily routine to improve the dissemination of risk information, as well as nursing performance.