Abstract

<p>Polycyclic Aromatic Hydrocarbons (PAHs) are a group of organic compounds found primarily in fossil fuels, such as gasoline, crude oil, and coal. These chemicals are also present in by-products of combustion, including asphalt, coal-tar pitch, and creosote, and are released during activities like coal conversion, burning of organic materials, and inefficient combustion processes. PAHs are also naturally emitted during forest fires and volcanic eruptions. Given their widespread presence in both industrial and natural environments, PAHs are of significant concern due to their potential health effects on humans, especially those exposed to elevated levels in polluted air or occupational settings. PAHs are often bound to particulate matter, such as diesel exhaust particles (DEP), which facilitates their transport in the atmosphere and enhances their inhalation risk. Studies have demonstrated the prevalence of specific PAHs, such as pyrene and phenanthrene, in outdoor air, emphasizing their potential health implications. The exposure to PAHs has been associated with various hematological abnormalities, including changes in blood parameters, which may serve as indicators of systemic toxicity. This review aims to explore the effects of PAH exposure on hematological parameters, with a particular focus on individuals working in environments with high PAH concentrations. Understanding these effects is crucial for developing appropriate mitigation strategies to reduce health risks in affected populations.</p>